Navigation auf uzh.ch

Suche

Department of Evolutionary Biology and Environmental Studies

Andreas Wagner

Research interests

Evolutionary innovation and adaptation in genes, genomes, and molecular networks; genetic robustness and evolvability; evolution by gene duplication; cryptic variation; cooperation and innovation in molecular systems; evolutionary dynamics of transposable elements; conceptual foundations of evolutionary theory; systems biology and evolution of regulatory and signaling circuits

CV

Education and professional positions

2011 - present Professor, Department of Evolutionary Biology and Environmental Studies, University Zurich, Switzerland
2016 - 2020 Director, Dept. of Evolutionary Biology and Environmental Studies
2021 Fellow, Stellenbosch Institute for Advanced Study (STIAS), South Africa
2007 - present Group Leader, Swiss Institute of Bioinformatics
2006 - 2010 Professor, Department of Biochemistry, University of Zurich, Switzerland
2002 - 2006 Associate Professor (tenured), Department of Biology, University of New Mexico, USA
2004 - 2005 Visiting Scientist, Institut des Hautes Études Scientifiques, Bures-sur-Yvette, France
1999 - present External Professor, The Santa Fe Institute, New Mexico, USA
1998 - 2002 Assistant Professor, Department of Biology, University of New Mexico, USA
1996 - 1998 Postdoctoral Fellow, The Santa Fe Institute, New Mexico, USA
1996 Visiting Scientist, Los Alamos National Laboratory, USA
1995 - 1996 Fellow, Institute for Advanced Study, Berlin, Germany
1991 - 1995 Ph.D., Department of Biology, Yale University, USA
1994 M. Phil., Department of Biology, Yale University, USA
1990 M.Sc., Department of Molecular Genetics, University of Vienna, Austria

Selected publications


See complete publication list on Andreas Wagner Lab

  • Papkou, A., Garcia-Pastor, L., Escudero, J.A., Wagner, A. (2023) A rugged yet easily navigable fitness landscape of antibiotic resistance. Science 382, eadh3860. DOI: 10.1101/2023.02.27.530293
  • Wagner, A. (2023) Evolvability-enhancing mutations in the fitness landscape of an RNA and a protein. Nature Communications 14, 3624. DOI: 10.1038/s41467-023-39321-8
  • Karve, S., Dasmeh, P., Zheng, J., Wagner, A. (2022) Low protein expression enhances phenotypic evolvability by intensifying selection on folding stability. Nature Ecology and Evolution 6, 1155—1164. DOI: 10.1038/s41559-022-01797-w
  • Toll-Riera, M., Olombrada, M., Castro-Giner, F., Wagner, A. (2022) A limit on the evolutionary rescue of an Antarctic bacterium from rising temperatures. Science Advances 8, eabk3511
    DOI: 10.1126/sciadv.abk3511
  • Zheng, J., Guo, N., Wagner, A. (2020) Strong selection enhances protein evolvability by increasing mutational robustness and foldability. Science 370, 6521 DOI: 10.1126/science.abb5962
  • van Gestel, J., Ackermann, M., Wagner, A. (2019) Microbial life cycles link global modularity in regulation to mosaic evolution. Nature Ecology and Evolution 3, 1184-1196 DOI: 10.1038/s41559-019-0939-6
  • Payne, J.L., Wagner, A. (2019) The causes of evolvability and their evolution. Nature Reviews Genetics 20, 24–38. DOI: 10.1038/s41576-018-0069-z

Weiterführende Informationen

Andreas Wagner

Andreas Wagner

Full Professor

Department of Evolutionary Biology and Environmental Studies
University of Zurich
Winterthurerstrasse 190
8057 Zurich

Office: Y27-J-54
Phone: +41 44 635 6141